Press Releases  | 22 Feb 2021

HKUST Decodes a Deep-sea Vent-endemic Snail Hologenome and Unveils its Living Strategies in the Extreme Environment

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(This article was published on EurekAlert! on February 19, 2021)

 

A research team led by Prof. QIAN Peiyuan, Head and Chair Professor from the Hong Kong University of Science and Technology (HKUST)’s Department of Ocean Science and David von Hansemann Professor of Science, has published their cutting-edge findings of symbiotic mechanisms of a deep-sea vent snail (Gigantopelta aegis) in the scientific journal Nature Communications. They discovered that Gigantopelta snail houses both sulfur-oxidizing bacteria and methane-oxidizing bacteria inside its esophageal gland cells (part of digestive system) as endosymbionts. By decoding the genomes of both snail host and two symbionts, Prof. Qian’s team disclosed a novel dual symbiosis system and the molecular adaptation to the extreme environment, gaining a new understanding of the origin of life on Earth.

 

Deep-sea hydrothermal vent is characterized as extremely high hydrostatic pressure and darkness, and they can release fluids overheated by the Earth’s crust, with concentrated toxic heavy metals and chemical substances. These characteristics make hydrothermal vent one of the most uniquely extreme environments on our planet. In addition, the deep-sea hydrothermal vent environment is very similar to the earth’s early environment, when life began to form. Unlike most ecosystems relying on photosynthesis-derived nutrients, fauna living in vents depend on chemosynthetic microbes that can utilize chemical energy to synthesize organic compounds, supporting dense and unique macro-organisms living there. However, how the organisms thrive and adapt to such an extreme environment remains a complex puzzle.

 

In April and May 2019, Prof. Qian’s team undertook a deep-sea research expedition and explored Longqi vent filed on the Southwest Indian Ridge with a remotely operated vehicle. They found a dominant species, Gigantopelta snails, at the sea floor (approximate 2800 m depth). Prof. Qian’s team discovered two types of symbiotic bacteria with dramatically different morphologies that live inside the esophageal gland cells of Gigantopelta snails, which was further identified as one sulfur-oxidizing bacteria and one methane-oxidizing bacteria. 

 

The team further decoded the genomes of Gigantopelta snail, sulfur-oxidizing bacteria and methane-oxidizing bacteria, unveiling a novel dual symbiosis system that are highly versatile in utilizing the chemical energy for nutrient synthesis. The sulfur-oxidizing bacteria can utilize the chemical energy from hydrogen, hydrogen sulfide, sulfate, sulfite and thiosulfate, while the methane-oxidizing bacteria can utilize hydrogen and methane. From the host side, there are more copies of pattern recognition receptors in Gigantopelta genome, and they specifically expressed in the symbiotic organ, which help Gigantopelta recognize and maintain a dual symbiosis system. Gigantopelta snails adopt a mutualistic metabolic relationship among multiple symbiotic partners and thus flourish in this vent ecosystem. These findings not only  enable us to gain a better understanding of how animals thrive in such extreme environment, but also shed light on how such animals cope with microbes in a highly specialized way. 

A large quantity of Gigantopelta aegis snails living in ‘Tiamat’ chimney in the Longqi vent field on the Southwest Indian Ridge
A large quantity of Gigantopelta aegis snails living in ‘Tiamat’ chimney in the Longqi vent field on the Southwest Indian Ridge
Gigantopelta aegis (Photo credit: Dr. CHEN Chong from JAMSTEC)
Gigantopelta aegis (Photo credit: Dr. CHEN Chong from JAMSTEC)
Prof. QIAN (middle) visited the Japan Agency for Marine-Earth Science and Technology (JAMSTEC) in 2015.  Dr. SUN Jin (second right) from HKUST and Dr. CHEN Chong from JAMSTEC (first left) have also contributed to the research
Prof. Qian (middle) visited the Japan Agency for Marine-Earth Science and Technology (JAMSTEC) in 2015. Dr. SUN Jin (second right) from HKUST and Dr. CHEN Chong from JAMSTEC (first left) have also contributed to the research
Stock photo of Prof. QIAN Peiyuan (third right, first row), his postdoctoral fellow Dr. LAN Yi (second right, first row) and other members of the research team.
Stock photo of Prof. Qian Peiyuan (third right, first row), his postdoctoral fellow Dr. Lan Yi (second right, first row) and other members of the research team.

About The Hong Kong University of Science and Technology
The Hong Kong University of Science and Technology (HKUST) (www.ust.hk) is a world-class research university that focuses on science, technology and business as well as humanities and social science.  HKUST offers an international campus, and a holistic and interdisciplinary pedagogy to nurture well-rounded graduates with global vision, a strong entrepreneurial spirit and innovative thinking.  HKUST attained the highest proportion of internationally excellent research work in the Research Assessment Exercise 2014 of Hong Kong’s University Grants Committee, and is ranked as the world’s best young university in Times Higher Education’s Young University Rankings 2019.  Its graduates were ranked 16th worldwide and top in Greater China in Global University Employability Survey 2018.